Glanzmann C, Horst W
Nucl Med (Stuttg). 1975 Aug 31;14(3):207-18.
About 100 patients with hyperthyroidism and diffuse goiter (gland weight not more than 60 g) were treated with an individually calculated dose of 125-Iodine. After a follow-up time between 1.5 and 2 years there are the following results: 82% of the patients are euthyroid and 18% are still hyperthyroid. Relapse rate was 10%. More than 30% of the residual or relapse hyperfunctions were T3 toxicosis. The status of 125-Iodine in the treatment of thyrotoxicosis is discussed with regard to the necessity of a "destructive" therapy in the major part of the patients. Published results of 125-Iodine therapy are summarized.
约100例甲状腺功能亢进症合并弥漫性甲状腺肿(腺体重量不超过60克)患者接受了个体化计算剂量的125碘治疗。经过1.5至2年的随访,结果如下:82%的患者甲状腺功能正常,18%仍为甲状腺功能亢进。复发率为10%。残留或复发的功能亢进中,超过30%为T3型甲状腺毒症。针对大部分患者进行“破坏性”治疗的必要性,讨论了125碘在甲状腺毒症治疗中的地位。总结了已发表的125碘治疗结果。