Wiklund Urban, Akay Metin, Morrison Stuart, Niklasson Urban
Department of Biomedical Engineering and Informatics, University Hospital, Umeå, Sweden.
IEEE Trans Biomed Eng. 2002 Jul;49(7):651-61. doi: 10.1109/TBME.2002.1010848.
In this paper, the discrete wavelet transform (DWT) was applied to analyze the fluctuations in RR interval and systolic arterial pressure (SAP) recorded from eight alpha-chloralose anesthetized pigs. Our aim was to characterize the autonomic modulation before and after cardiac autonomic blockade and during baroreflex function tests. The instantaneous power of decomposed low-frequency (LF) and high-frequency (HF) components was used for a time-variant spectral analysis. Our results suggested that transient events and changes in autonomic modulation were detected with high temporal resolution. A nonlinear relationship between RR interval and SAP during pharmacologically induced changes in blood pressure was found, when the superimposed effect of respiratory sinus arrhythmia was removed. In addition, the baroslopes were nearly linear when both the LF and HF components were removed using DWT decomposition.
在本文中，离散小波变换（DWT）被用于分析从八只α-氯醛糖麻醉猪记录的RR间期和收缩期动脉压（SAP）的波动情况。我们的目的是表征心脏自主神经阻滞前后以及压力感受性反射功能测试期间的自主神经调节。分解后的低频（LF）和高频（HF）成分的瞬时功率用于时变频谱分析。我们的结果表明，能够以高时间分辨率检测到自主神经调节中的瞬态事件和变化。当去除呼吸性窦性心律不齐的叠加效应时，发现在药理学诱导的血压变化过程中RR间期与SAP之间存在非线性关系。此外，使用DWT分解去除LF和HF成分后，压力感受性斜率几乎呈线性。
