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性功能障碍与抑郁症:病因、患病率及治疗

Sexual dysfunction and depression: etiology, prevalence, and treatment.

作者信息

Shabsigh R, Zakaria L, Anastasiadis A G, Seidman A S

机构信息

Department of Urology, Columbia-Presbyterian Medical Center, 161 Fort Washington Avenue, New York, NY 10032, USA.

出版信息

Curr Urol Rep. 2001 Dec;2(6):463-7. doi: 10.1007/s11934-001-0040-x.

DOI:10.1007/s11934-001-0040-x
PMID:12084232
Abstract

Sexual dysfunction and depression are very common conditions that are age-related and chronic. In men, epidemiologic studies have confirmed a strong correlation between erectile dysfunction and symptoms of depression. Both conditions have a significant negative impact on the quality of life of patients and their partners. Several studies showed that restoration of normal sexual function improves the quality of life of patients and their partners, regardless of treatment method. The literature review and recent observations emphasize the multifactorial nature of sexual dysfunction and, more specifically, erectile dysfunction and underline the importance of the comorbidity and bidirectional relationship between erectile dysfunction and depression. Research is progressing on the possible link between andropause, sexual dysfunction, and depression, thus opening potential new opportunities to address issues of aging-related morbidities.

摘要

性功能障碍和抑郁症是非常常见的与年龄相关的慢性疾病。在男性中,流行病学研究证实勃起功能障碍与抑郁症状之间存在密切关联。这两种病症都会对患者及其伴侣的生活质量产生重大负面影响。多项研究表明,无论采用何种治疗方法,恢复正常性功能都能改善患者及其伴侣的生活质量。文献综述和近期观察强调了性功能障碍,尤其是勃起功能障碍的多因素性质,并强调了勃起功能障碍与抑郁症合并症及双向关系的重要性。关于更年期、性功能障碍和抑郁症之间可能联系的研究正在取得进展,从而为解决与衰老相关的发病问题开辟了潜在的新机会。

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本文引用的文献

1
Treatment of erectile dysfunction in men with depressive symptoms: results of a placebo-controlled trial with sildenafil citrate.伴有抑郁症状男性勃起功能障碍的治疗:枸橼酸西地那非安慰剂对照试验的结果
Am J Psychiatry. 2001 Oct;158(10):1623-30. doi: 10.1176/appi.ajp.158.10.1623.
2
The mutually reinforcing triad of depressive symptoms, cardiovascular disease, and erectile dysfunction.抑郁症状、心血管疾病和勃起功能障碍之间相互强化的三联征。
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Psychiatric Comorbidity, Sexual Dysfunction, and Quality of Life in Patients Undergoing Hemodialysis: A Case-Control Study.血液透析患者的精神共病、性功能障碍与生活质量:一项病例对照研究。
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The impact of psychosocial factors on the risk of erectile dysfunction and inhibition of sexual desire in a sample of the Brazilian population.心理社会因素对巴西人群样本中勃起功能障碍风险及性欲抑制的影响。
Sao Paulo Med J. 2005 Jan 2;123(1):11-4. doi: 10.1590/s1516-31802005000100003. Epub 2005 Mar 31.
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Are subjects with erectile dysfunction aware of their condition? Results from a retrospective study based on an Italian free-call information service.
J Endocrinol Invest. 2004 Jun;27(6):548-56. doi: 10.1007/BF03347477.
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Causes of erectile dysfunction.勃起功能障碍的原因。
Endocrine. 2004 Mar-Apr;23(2-3):119-23. doi: 10.1385/ENDO:23:2-3:119.
性活动与心脏风险:抑郁症是一个促成因素吗?
Am J Cardiol. 2000 Jul 20;86(2A):38F-40F. doi: 10.1016/s0002-9149(00)00891-2.
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Report of the international consensus development conference on female sexual dysfunction: definitions and classifications.女性性功能障碍国际共识发展会议报告:定义与分类
J Urol. 2000 Mar;163(3):888-93.
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Andropause: a misnomer for a true clinical entity.
J Urol. 2000 Mar;163(3):705-12. doi: 10.1016/s0022-5347(05)67788-9.
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Sexual dysfunction in the United States: prevalence and predictors.美国的性功能障碍:患病率及预测因素。
JAMA. 1999 Feb 10;281(6):537-44. doi: 10.1001/jama.281.6.537.
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Depression and the risk of coronary heart disease in the Normative Aging Study.标准衰老研究中的抑郁症与冠心病风险
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