Hormonal regulation of the epithelial sodium channel ENaC: N or P(o)?
作者信息
Rossier Bernard C
机构信息
Institute of Pharmacology and Toxicology, University of Lausanne, Lausanne CH-1005, Switzerland.
出版信息
J Gen Physiol. 2002 Jul;120(1):67-70. doi: 10.1085/jgp.20028638.
Abstract
摘要
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Hormonal regulation of the epithelial sodium channel ENaC: N or P(o)?上皮钠通道ENaC的激素调节：N还是P（o）？
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本文引用的文献
1
cAMP increases density of ENaC subunits in the apical membrane of MDCK cells in direct proportion to amiloride-sensitive Na(+) transport.环磷酸腺苷（cAMP）增加了MDCK细胞顶端膜中上皮钠通道（ENaC）亚基的密度，且与氨氯地平敏感的钠（Na⁺）转运成正比。
J Gen Physiol. 2002 Jul;120(1):71-85. doi: 10.1085/jgp.20018547.
2
Effects of aldosterone on biosynthesis, traffic, and functional expression of epithelial sodium channels in A6 cells.醛固酮对A6细胞中上皮钠通道生物合成、转运及功能表达的影响。
J Gen Physiol. 2002 May;119(5):427-42. doi: 10.1085/jgp.20028559.
3
Cell-surface expression of the channel activating protease xCAP-1 is required for activation of ENaC in the Xenopus oocyte.爪蟾卵母细胞中，通道激活蛋白酶xCAP-1的细胞表面表达是ENaC激活所必需的。
J Am Soc Nephrol. 2002 Mar;13(3):588-594. doi: 10.1681/ASN.V133588.
4
Trafficking and cell surface stability of the epithelial Na+ channel expressed in epithelial Madin-Darby canine kidney cells.上皮性钠通道在上皮性犬肾细胞中的转运及细胞表面稳定性
J Biol Chem. 2002 Mar 22;277(12):9772-9. doi: 10.1074/jbc.M110904200. Epub 2001 Dec 28.
5
Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression.Sgk1对Nedd4-2的磷酸化作用调节上皮钠离子通道的细胞表面表达。
EMBO J. 2001 Dec 17;20(24):7052-9. doi: 10.1093/emboj/20.24.7052.
6
Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel.血清和糖皮质激素调节激酶调节Nedd4-2介导的上皮钠通道抑制作用。
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Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK.醛固酮诱导肾集合系统早期ENaC快速向顶端移位：SGK的可能作用。
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Am J Physiol Renal Physiol. 2001 Jan;280(1):F112-8. doi: 10.1152/ajprenal.2001.280.1.F112.
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Differential subcellular localization of ENaC subunits in mouse kidney in response to high- and low-Na diets.小鼠肾脏中上皮钠通道（ENaC）亚基在高钠和低钠饮食条件下的亚细胞定位差异。
Am J Physiol Renal Physiol. 2000 Aug;279(2):F252-8. doi: 10.1152/ajprenal.2000.279.2.F252.
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