Lee Moon Sung, Cho Joo Young, Cheon Young Koog, Ryu Chang Beom, Moon Jong Ho, Cho Young Deok, Kim Jin Oh, Kim Yun Soo, Lee Joon Seong, Shim Chan Sup
Department of Internal Medicine, Institute for Digestive Research, Soon Chun Hyang University, College of Medicine, Seoul, Korea.
Gastrointest Endosc. 2002 Jul;56(1):83-8. doi: 10.1067/mge.2002.125104.
Bleeding from gastric varices larger than 2 cm in diameter represents a major limitation for endoscopic hemostasis.
Endoscopic ligation of gastric varices was performed with detachable snares and elastic bands in 41 patients who had recent bleeding from gastric varices larger than 2 cm in diameter. Gastric varices larger than 2 cm were ligated with detachable snares, and then adjacent small gastric varices were ligated with elastic bands.
Among the 41 patients, 10 of 12 patients with active bleeding and 28 of 29 patients with red color signs at initial endoscopy were successfully treated by endoscopic ligation by using detachable snares and elastic bands. Bleeding recurred early (before variceal eradication) in 4 of 38 patients (10.5%). The overall hemostatic rate for endoscopic ligation was 82.9% (34/41). In 33 of 36 patients (91.7%) who underwent repeated ligation treatments, variceal eradication was nearly complete. Mean follow-up in 30 of 33 patients after eradication of varices was 16.4 months (3-32 months), and 29 of 30 did not have recurrent bleeding. During and after ligation there were no serious complications.
Endoscopic ligation therapy with large detachable snares and elastic bands is safe and effective for treatment of large bleeding gastric varices.
直径大于2 cm的胃静脉曲张出血是内镜止血的主要限制因素。
对41例近期有直径大于2 cm的胃静脉曲张出血的患者,使用可脱性圈套器和弹力圈进行内镜下胃静脉曲张结扎术。先用可脱性圈套器结扎直径大于2 cm的胃静脉曲张,然后用弹力圈结扎相邻的小胃静脉曲张。
41例患者中,12例活动性出血患者中的10例以及初次内镜检查时有红色征的29例患者中的28例,通过使用可脱性圈套器和弹力圈进行内镜结扎成功治疗。38例患者中有4例(10.5%)在早期(静脉曲张根除前)出血复发。内镜结扎的总体止血率为82.9%(34/41)。在接受重复结扎治疗的36例患者中的33例(91.7%),静脉曲张几乎完全根除。33例患者中有30例在静脉曲张根除后平均随访16.4个月(3 - 32个月),30例中的29例未再出血。结扎期间及之后无严重并发症。
使用大型可脱性圈套器和弹力圈进行内镜结扎治疗大出血性胃静脉曲张安全有效。