Young Brian A, Gruber Tanja M, Gross Carol A
Department of Biochemistry and Biophysics, University of California, San Francisco, 94143, USA.
Cell. 2002 May 17;109(4):417-20. doi: 10.1016/s0092-8674(02)00752-3.
Initiation of transcription is the first step in gene expression and a major point of regulation. Recent structural studies reveal the nature of the initiating complex and suggest new ways of accomplishing the processes required for initiation.
转录起始是基因表达的第一步，也是一个主要的调控点。最近的结构研究揭示了起始复合物的性质，并提出了完成起始所需过程的新方法。
