Gillespie Theresa W
Clin J Oncol Nurs. 2002 Jul-Aug;6(4):206-11. doi: 10.1188/02.CJON.206-211.
Significant progress has been made in the prevention and management of many symptoms associated with cancer and its therapy. However, cancer-related anemia, which may affect more than half of all patients with cancer, often is assessed and treated inadequately. Severe anemia not only causes significant symptomology but also may impair functional status and quality of life. In addition, anemia has been found to affect treatment outcomes, including disease-free and overall survival. Therapeutic strategies, based on the underlying etiology of anemia, include iron supplementation, blood transfusion, and administration of recombinant human erythropoietin. Future approaches may involve novel agents under investigation that are designed to address current concerns related to efficacy, convenience, and possible cost-effectiveness of treatment of cancer-related anemia.
在癌症及其治疗相关的许多症状的预防和管理方面已取得重大进展。然而，癌症相关贫血可能影响超过一半的癌症患者，其评估和治疗往往不充分。严重贫血不仅会导致明显的症状，还可能损害功能状态和生活质量。此外，已发现贫血会影响治疗结果，包括无病生存期和总生存期。基于贫血潜在病因的治疗策略包括补充铁剂、输血和给予重组人促红细胞生成素。未来的方法可能涉及正在研究的新型药物，这些药物旨在解决当前与癌症相关贫血治疗的疗效、便利性和可能的成本效益相关的问题。
