Zamfir C L, Nechifor M, Indrei A, Indrei L L, Mihalache G
Disciplina de Histologie, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr. T. Popa Iaşi.
Rev Med Chir Soc Med Nat Iasi. 2000 Oct-Dec;104(4):137-9.
The role of prostaglandins and their synthetic analogous at the level of the female genital system is multiple. The synthetic analogous of the prostaglandin F2 alpha are utilised in a large area of treatments, for multiple purposes, but their influence on the lung is not so well known. The study was made on 2 lots with 12 non pregnant female rats: the first lot was the witness lot and didn't receive any substance. The second lot received 25 micrograms/kg/day Flavoliz (synthetic analogous of the prostaglandin F2 alpha). The prostaglandinic analogous produces vasodilating effects on the lung blood vessels and moderate pulmonary destruction.
前列腺素及其合成类似物在女性生殖系统层面具有多种作用。前列腺素F2α的合成类似物被广泛应用于多个治疗领域，但它们对肺部的影响尚不十分清楚。该研究以两组各12只未孕雌性大鼠为对象：第一组为对照组，未接受任何物质。第二组接受25微克/千克/天的氟前列素（前列腺素F2α的合成类似物）。这种前列腺素类似物对肺血管有血管舒张作用，并造成中度肺损伤。
