Heintze Siegward D, Twetman Svante
Ivoclar, Schaan, Liechtenstein, Sweden.
Am J Dent. 2002 Apr;15(2):103-8.
To evaluate the suppressive effect of four different chlorhexidine (CHX) regimens on the interdental levels of mutans streptococci (MS) on enamel and various restorative materials in a group of adults.
128 subjects with high salivary MS counts were allocated to (A) a single professional tooth cleaning with a 1% CHX gel, (B) duplicate applications of a dental varnish containing 1% CHX and 1% thymol, (C) a single application of a 40% CHX varnish, (D) daily tooth brushing with a 1% CHX gel for 2 weeks . Interdental plaque samples were collected at baseline, 1 week, and 3 months after termination of CHX treatment.
The baseline MS levels were significantly higher in plaque from composite surfaces than in plaque from enamel surfaces. All methods decreased the interdental MS levels compared with the baseline on enamel, composite and amalgam surfaces. On both clinically sound enamel and amalgam surfaces, the outcomes in Groups B, C and D were similar and significantly better than in Group A. On composite surfaces, the 40% CHX varnish (C) and the CHX brushing (D) were significantly more effective in decreasing MS than the low-CHX varnish (B) and the professional CHX cleaning (A).
评估四种不同洗必泰（CHX）方案对一组成年人牙釉质及各种修复材料上变形链球菌（MS）龈间水平的抑制作用。
128名唾液中MS计数较高的受试者被分配至以下组：（A）用1% CHX凝胶进行单次专业牙齿清洁；（B）重复应用含1% CHX和1%百里酚的牙用清漆；（C）单次应用40% CHX清漆；（D）用1% CHX凝胶每天刷牙2周。在CHX治疗开始前、治疗结束后1周和3个月收集龈间菌斑样本。
复合树脂表面菌斑中的基线MS水平显著高于牙釉质表面菌斑中的基线MS水平。与牙釉质、复合树脂和汞合金表面的基线相比，所有方法均降低了龈间MS水平。在临床健康的牙釉质和汞合金表面，B、C和D组的结果相似，且显著优于A组。在复合树脂表面，40% CHX清漆（C组）和CHX刷牙（D组）在降低MS方面比低CHX清漆（B组）和专业CHX清洁（A组）显著更有效。
