Belsha Craig W.
St. Louis University Department of Pediatrics, Cardinal Glennon Children's Hospital, 1465 S. Grand Boulevard, St. Louis, MO 63104, USA.
Curr Treat Options Cardiovasc Med. 2002 Aug;4(4):351-360. doi: 10.1007/s11936-002-0015-3.
Recognition of systemic hypertension in children and adolescents requires careful blood pressure measurement using proper technique to compare with appropriate normative data. Selected use of ambulatory blood pressure monitoring can identify children with "white coat" hypertension, thus avoiding unnecessary diagnostic testing and treatment in these children. Nonpharmacologic therapies including dietary sodium restriction, weight loss, and exercise may benefit children and adolescents with borderline hypertension and mild essential hypertension. These therapies may be important adjunctive agents in children requiring antihypertensive therapy as well. Historically, pharmacologic management of hypertension in children has been limited by a lack of controlled studies and age-appropriate formulations. Recent clinical trials have provided new information regarding a number of antihypertensive agents in this age group.
识别儿童和青少年的系统性高血压需要使用适当的技术仔细测量血压,以便与合适的标准数据进行比较。选择性地使用动态血压监测可以识别出患有“白大衣”高血压的儿童,从而避免对这些儿童进行不必要的诊断测试和治疗。包括饮食中限制钠摄入、减肥和运动在内的非药物疗法可能对患有临界高血压和轻度原发性高血压的儿童和青少年有益。这些疗法对于需要抗高血压治疗的儿童来说也可能是重要的辅助药物。从历史上看,儿童高血压的药物治疗一直受到缺乏对照研究和适合年龄剂型的限制。最近的临床试验提供了有关该年龄组多种抗高血压药物的新信息。