对母体环境进行干预可逆转具有遗传易感性大鼠的牙周炎。
Manipulations in maternal environment reverse periodontitis in genetically predisposed rats.
作者信息
Sluyter Frans, Breivik Torbjørn, Cools Alexander
机构信息
SGDP Research Centre, Institute of Psychiatry, London, United Kingdom.
出版信息
Clin Diagn Lab Immunol. 2002 Jul;9(4):931-2. doi: 10.1128/cdli.9.4.931-932.2002.
Abstract
The predisposition to develop periodontitis is partly genetically determined in humans as well as in animals. Here we demonstrate, however, that early manipulations in the maternal environment of an animal (rat) model of periodontitis can fully reverse the genetic predisposition to develop periodontitis at adult age.
摘要
人类和动物患牙周炎的易感性部分由基因决定。然而，我们在此证明，在牙周炎动物（大鼠）模型的母体环境中进行早期干预，可以完全逆转成年后患牙周炎的遗传易感性。
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