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[泪阜双侧痣]

[Bilateral nevus of the caruncle].

作者信息

Viestenz Anja, Cursiefen Claus, Küchle Michael

机构信息

Augenklinik mit Poliklinik der Universität Erlangen-Nürnberg, Erlangen.

出版信息

Klin Monbl Augenheilkd. 2002 May;219(5):380-2. doi: 10.1055/s-2002-32628.

Abstract

BACKGROUND

Pathologic processes of the caruncle are relatively rare with a predominance of papillomas, pyogenic granulomas and nevi.

PATIENT

A 22 year old Caucasian male patient presented with bilateral hyperpigmentations of the caruncle. They had first been observed at an age of seven and showed slight progression in size and colour with time. Examination revealed hyperpigmentation with clear pseudocystic spaces. The tarsal or bulbar conjunctiva was not involved. An excision of both processes was performed.

HISTOLOGY

Light microscopy revealed nests of nevus cells with melanin granules and round basophilic nuclei as well as gland ducts and sebaceous glands, beneath and within the multilayered keratinizing and nonkeratinizing squamous epithelium. The sections revealed a bilateral melanocytic compound nevus of the caruncle.

DISCUSSION

To our knowledge, there is no report on bilateral nevi of the caruncle among the Caucasian population. The possibility of a common precursor cell during the embryologic development causing the bilaterality is discussed.

摘要

背景

泪阜的病理过程相对罕见,以乳头状瘤、化脓性肉芽肿和痣为主。

患者

一名22岁的白种男性患者,双侧泪阜色素沉着。色素沉着最早在7岁时被发现,随着时间推移,大小和颜色略有变化。检查发现色素沉着伴有清晰的假囊肿腔隙。睑结膜或球结膜未受累。对双侧病变进行了切除。

组织学检查

光学显微镜下可见痣细胞巢,含有黑色素颗粒和圆形嗜碱性细胞核,以及多层角化和非角化鳞状上皮下方及内部的腺管和皮脂腺。切片显示双侧泪阜黑素细胞复合痣。

讨论

据我们所知,白种人群中尚无双侧泪阜痣的报道。本文讨论了胚胎发育过程中共同前体细胞导致双侧病变的可能性。

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