Groh M J, Holbach L M
Augenklinik mit Poliklinik, Universität Erlangen-Nürnberg.
Klin Monbl Augenheilkd. 1999 Oct;215(4):263-5. doi: 10.1055/s-2008-1034712.
Congenital divided nevi of the eyelids are a rare melanocytic lesion. Only 30 patients are reported in literature. We report on a 6-year-old boy and a 41-year-old male with this lesion and give a short overview of the literature.
Patient 1: A 6-year-old boy presented with a pigmented divided nevus of the left eye involving the upper and lower lid naselly. The lesion had increased in size in the last one year. Otherwise the results of ophthalmological examination were unremarkable. The divided nevus was completely excised. Histopathological studies revealed a melanocytic compound nevus. Patient 2: A 41-year old male presented in our department with a divided pigmented nevus on his left eye involving the upper and lower lid laterally. The lesion had gradually increased since birth. Otherwise the results of ophthalmological examination were unremarkable. A subtotoal excision and debulking procedure was performed. The defect in the lower eyelid was covered using a transposition flap from the upper eyelid. Histopathological examination revealed a melanocytic compound nevus.
Divided nevi of the eyelids may be disfiguring and include the possibility of deprivation amblyopia when reaching a certain size in childhood. Malignant changes of this lesion were not observed so far. Total excision or subtotal excision and a debulking procedure may be helpful.
先天性眼睑分裂痣是一种罕见的黑素细胞病变。文献中仅报道了30例患者。我们报告了一名6岁男孩和一名41岁男性患有这种病变,并对文献进行简要概述。
患者1:一名6岁男孩,左眼出现色素沉着的分裂痣,累及鼻侧的上下眼睑。该病变在过去一年中增大。眼科检查结果其他方面无异常。分裂痣被完全切除。组织病理学研究显示为黑素细胞复合痣。患者2:一名41岁男性,因左眼外侧上下眼睑的分裂色素痣到我院就诊。该病变自出生以来逐渐增大。眼科检查结果其他方面无异常。进行了次全切除和减容手术。下眼睑的缺损用来自上眼睑的转位皮瓣覆盖。组织病理学检查显示为黑素细胞复合痣。
眼睑分裂痣可能会影响容貌,并且在儿童时期达到一定大小时存在剥夺性弱视的可能性。迄今为止未观察到该病变的恶性变化。全切除或次全切除及减容手术可能会有帮助。