Anderson Davina M, White Richard A S
Queens Veterinary School Hospital, Cambridge University, Cambridge, England.
Vet Surg. 2002 Jul-Aug;31(4):303-8. doi: 10.1053/jvet.2002.33597.
To describe the clinical and morphologic characteristics of nasal dermoid sinus cysts in the dog.
Retrospective clinical study.
Six client-owned dogs.
Medical records (1995 to 1999) of 6 dogs that had a discharging sinus in the midline of the nose removed surgically were reviewed for signalment, physical examination, surgical and histopathologic findings, and outcome.
Three golden retrievers, 1 springer spaniel, 1 cocker spaniel, and 1 Brittany spaniel with a history of intermittent discharge from a small opening in the midline on the bridge of the nose at the junction between the nasal planum and the skin were identified. The condition was unresponsive to antibiotic therapy, and previous surgical excision had been unsuccessful in 3 dogs. None of the dogs had any other congenital defects, and all dogs responded to complete surgical excision of the tract and cyst. On histopathologic examination of excised tissue, there were adnexal structures along a tract lined with stratified squamous epithelium, consistent with a developmental abnormality of ectodermal tissue.
The lesions were diagnosed as nasal dermoid sinus cysts, similar to the congenital condition described in humans. Nasal dermoid sinus cysts are rare developmental defects related to abnormal development of the pre-nasal space and may extend into the cranial vault causing cerebral abscesses or recurrent meningitis. Complete surgical excision has a good prognosis.
This is a new condition that should be added to the surgical differential diagnosis for a discharging sinus over the external nares in dogs.
描述犬鼻皮样窦囊肿的临床和形态学特征。
回顾性临床研究。
6只客户拥有的犬。
回顾了1995年至1999年6只因鼻部中线有排液窦而接受手术切除的犬的病历,包括信号史、体格检查、手术和组织病理学检查结果及预后情况。
确定了3只金毛寻回犬、1只激飞猎犬、1只可卡犬和1只不列塔尼猎犬,它们有在鼻平面与皮肤交界处鼻梁中线的一个小开口间歇性排液的病史。该病症对抗生素治疗无反应,3只犬之前的手术切除未成功。所有犬均无其他先天性缺陷,且所有犬对窦道和囊肿的完全手术切除均有反应。对切除组织进行组织病理学检查时,在一条由复层鳞状上皮衬里的窦道沿线有附属结构,符合外胚层组织的发育异常。
这些病变被诊断为鼻皮样窦囊肿,类似于人类描述的先天性病症。鼻皮样窦囊肿是与鼻前间隙异常发育相关的罕见发育缺陷,可能延伸至颅腔导致脑脓肿或复发性脑膜炎。完全手术切除预后良好。
这是一种新的病症,应添加到犬外鼻孔排液窦的手术鉴别诊断中。