Riley Roger S, Ben-Ezra Jonathan M, Tidwell Ann, Romagnoli Gina
Department of Pathology, Medical College of Virginia, Hospitals of Virginia Commonwealth University, 403 North 13th Street, Richmond, VA 23298, USA.
Hematol Oncol Clin North Am. 2002 Apr;16(2):373-420, vii. doi: 10.1016/s0889-8588(02)00005-9.
Enumeration of peripheral blood reticulocytes is an essential part of the diagnosis and management of anemic patients, since the number of reticulocytes in the peripheral blood reflects the erythrocytic activity of the bone marrow. Reticulocyte enumeration using flow cytometric methodology is rapidly replacing the inaccurate, imprecise manual counting technique used in the past. This article explores the pathophysiology of the reticulocyte, the various means of counting reticulocytes, and the diverse clinical applications of reticulocyte data.
外周血网织红细胞计数是贫血患者诊断和管理的重要组成部分，因为外周血中网织红细胞的数量反映了骨髓的红细胞生成活性。使用流式细胞术方法进行网织红细胞计数正在迅速取代过去使用的不准确、不精确的手工计数技术。本文探讨了网织红细胞的病理生理学、计数网织红细胞的各种方法以及网织红细胞数据的多种临床应用。
