抗癫痫药物选择中的治疗策略。

Therapeutic strategies in the choice of antiepileptic drugs.

作者信息

de Borchgrave V, Delvaux V, de Tourchaninoff M, Dubru J M, Ghariani S, Grisar Th, Legros B, Ossemann M, Sadzot B, Tugendhaft P, Van Bogaert P, van Rijckevorsel K

机构信息

Groupe de travail des Centres Francophones de Référence de l'Epilepsie Réfractaire.

出版信息

Acta Neurol Belg. 2002 Mar;102(1):6-10.

PMID:12094563

Abstract

The choice of treatment of newly diagnosed epilepsy involves many factors such as age, sex, life style, general health and concomitant medication. The seizure type, syndrome, and the pharmacology, efficacy and safety of the antiepileptic drugs (AEDs) should also be considered. Some of the new AEDs appear to provide at least equivalent efficacy with better tolerability. Some of these drugs have the potential to become drugs of first choice in newly diagnosed epilepsy. At the present time, we also must consider the criteria of reimbursement of these drugs. In this paper, we try to describe common and practical strategies to start a treatment of newly diagnosed epilepsy.

摘要

新诊断癫痫的治疗选择涉及诸多因素，如年龄、性别、生活方式、总体健康状况及合并用药情况。还应考虑癫痫发作类型、综合征以及抗癫痫药物（AEDs）的药理学特性、疗效和安全性。一些新型AEDs似乎具有至少相当的疗效且耐受性更好。其中一些药物有可能成为新诊断癫痫的首选药物。目前，我们还必须考虑这些药物的报销标准。在本文中，我们试图描述开始治疗新诊断癫痫的常见实用策略。