Kniaz'kin I V, Iuzhakov V V, Chalisova N I, Grigor'ev E I
St. Petersburg Institute of Bioregulation and Gerontology, 3 Dynamo pr., 197110, St. Petersburg, Russia.
Adv Gerontol. 2002;9:110-5.
A synthetic dipeptide vilon (Lys-Glu, 20 ng/ml) was added to a cultural medium of explants taken from rats of 3 days, 3 weeks and 2 years of age. The peptide induced morphologic stability of the tissue and activated the regeneration and functional activity of cells. The stronger effect on the explants taken from the old rats suggests that vilon is a candidate for geriatric research and practice.
将合成二肽维隆(赖氨酸 - 谷氨酸,20纳克/毫升)添加到取自3日龄、3周龄和2岁龄大鼠的外植体培养基中。该肽诱导了组织的形态稳定性,并激活了细胞的再生和功能活性。对取自老年大鼠的外植体的作用更强,这表明维隆是老年医学研究和实践的一个候选物。