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[Cytocidal effects of gemtuzumab ozogamicin (CMA-676) on CD33-expressing acute myeloid leukemia cells, analysis P-glycoprotein and CD34 expression].

作者信息

Matsui Hirotaka, Takeshita Akihiro, Naito Kensuke, Onishi Kazunori, Ono Ryuzo

出版信息

Rinsho Ketsueki. 2002 May;43(5):309-15.

PMID:12096475
Abstract
摘要

相似文献

1
[Cytocidal effects of gemtuzumab ozogamicin (CMA-676) on CD33-expressing acute myeloid leukemia cells, analysis P-glycoprotein and CD34 expression].[吉妥单抗奥佐米星(CMA-676)对表达CD33的急性髓性白血病细胞的杀细胞作用、P-糖蛋白和CD34表达分析]
Rinsho Ketsueki. 2002 May;43(5):309-15.
2
Reduced effect of gemtuzumab ozogamicin (CMA-676) on P-glycoprotein and/or CD34-positive leukemia cells and its restoration by multidrug resistance modifiers.吉妥单抗奥唑米星(CMA-676)对P-糖蛋白和/或CD34阳性白血病细胞的作用减弱及其通过多药耐药调节剂的恢复。
Leukemia. 2002 May;16(5):813-9. doi: 10.1038/sj.leu.2402459.
3
Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukaemia in first relapse.吉妥珠单抗奥唑米星用于首次复发的CD33阳性急性髓系白血病患者的疗效和安全性。
Expert Opin Biol Ther. 2001 Sep;1(5):893-901. doi: 10.1517/14712598.1.5.893.
4
[Monoclonal antibody therapies for acute leukemia].
Rinsho Ketsueki. 2002 May;43(5):353-6.
5
Calicheamicin-conjugated humanized anti-CD33 monoclonal antibody (gemtuzumab zogamicin, CMA-676) shows cytocidal effect on CD33-positive leukemia cell lines, but is inactive on P-glycoprotein-expressing sublines.加利车霉素偶联的人源化抗CD33单克隆抗体(吉妥单抗,CMA-676)对CD33阳性白血病细胞系具有细胞杀伤作用,但对表达P-糖蛋白的亚系无活性。
Leukemia. 2000 Aug;14(8):1436-43. doi: 10.1038/sj.leu.2401851.
6
Cytotoxic activity of gemtuzumab ozogamicin (Mylotarg) in acute myeloid leukemia correlates with the expression of protein kinase Syk.吉妥单抗奥唑米星(麦罗塔)在急性髓系白血病中的细胞毒性活性与蛋白激酶Syk的表达相关。
Leukemia. 2006 Dec;20(12):2093-101. doi: 10.1038/sj.leu.2404437. Epub 2006 Oct 19.
7
The cytotoxic effects of gemtuzumab ozogamicin (mylotarg) in combination with conventional antileukemic agents by isobologram analysis in vitro.体外等辐射图分析联合常规抗白血病药物时吉妥珠单抗奥唑米星(美罗华)的细胞毒性作用。
Anticancer Res. 2009 Nov;29(11):4589-96.
8
Pharmacokinetics of gemtuzumab ozogamicin, an antibody-targeted chemotherapy agent for the treatment of patients with acute myeloid leukemia in first relapse.吉妥珠单抗奥唑米星的药代动力学,一种用于治疗首次复发的急性髓性白血病患者的抗体靶向化疗药物。
J Clin Pharmacol. 2001 Nov;41(11):1206-14. doi: 10.1177/00912700122012751.
9
Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse.吉妥珠单抗奥唑米星用于首次复发的CD33阳性急性髓系白血病患者的疗效和安全性。
J Clin Oncol. 2001 Jul 1;19(13):3244-54. doi: 10.1200/JCO.2001.19.13.3244.
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Gemtuzumab ozogamicin: promise and challenge in patients with acute myeloid leukemia.吉妥珠单抗奥唑米星:急性髓系白血病患者的希望与挑战
Expert Rev Anticancer Ther. 2002 Dec;2(6):630-40. doi: 10.1586/14737140.2.6.630.