Walstam R
Strahlentherapie. 1975 Sep;150(3):251-6.
Remote (controlled) afterloading installations, offer the possibility to improve the dose distributions of the different applicators, since this apparatus permits the employment of artificial radionuclides with a high specific activity and with low energy of gamma rays. It is therefore possible to incorporate effective shielding into the applicators. The possible individual fitting of the dose distribution, however, demands considerable clinical effort, as the extension of the tumor in question has to be ascertained with sufficient accuracy. Otherwise, underdosage to tumor cells may happen within the shielded area. Most afterloading techniques are using stiff applicators and geometrical fixation within patients; configuration and position of the radiation sources in the patient therefore remain unchanged during the whole irradiation. Thus, it becomes possible to adapt additional external irradiation more exactly than before to the intracavitary dose distribution.
遥控后装设备能够改善不同施源器的剂量分布,因为该设备允许使用比活度高且γ射线能量低的人工放射性核素。因此,可以在施源器中加入有效的屏蔽。然而,剂量分布的个体化调整需要大量的临床工作,因为必须足够准确地确定相关肿瘤的范围。否则,屏蔽区域内的肿瘤细胞可能会出现剂量不足的情况。大多数后装技术使用的是刚性施源器并在患者体内进行几何固定;因此,在整个照射过程中,患者体内辐射源的形状和位置保持不变。这样,就能够比以前更精确地使附加的外照射与腔内剂量分布相匹配。