Vangelova K, Israel M, Mihaylov S
Laboratory of Physiology, Psychology and Ergonomics, National Center of Hygiene, Medical Ecology and Nutrition, 15 Dimiter Nestorov Boul., 1431 Sofia, Bulgaria.
Cent Eur J Public Health. 2002 Jun;10(1-2):24-8.
The aim of the study was to investigate the effect of long term exposure to low level radiofrequency (RF) electromagnetic (EM) radiation on the excretion rates of stress hormones in satellite station operators during 24-hour shifts. Twelve male operators at a satellite station for TV communications and space research were studied during 24-hour shifts. Dosimetric evaluation of the exposure was carried out and showed low level exposure with specific absorption of 0.1127 J.kg-1. A control group of 12 unexposed male operators with similar job task and the same shift system were studied, too. The 11-oxycorticosteroids (11-OCS), adrenaline and noradrenaline were followed by spectrofluorimetric methods on 3-hour intervals during the 24-hour shifts. The data were analyzed by tests for interindividual analysis, Cosinor analysis and analysis of variance (ANOVA). Significant increase in the 24-hour excretion of 11-OCS and disorders in its circadian rhythm, manifested by increase in the mesor, decrease in the amplitude and shift in the acrophase were found in the exposed operators. The changes in the excretion rates of the catecholamines were significant and showed greater variability of both variables. The long term effect of the exposure to low-level RF EM radiation evoked pronounced stress reaction with changes in the circadian rhythm of 11-OCS and increased variability of catecholamines secretion. The possible health hazards associated with observed alteration in the stress system need to be clarified by identification of their significance and prognostic relevance.
本研究的目的是调查长期暴露于低水平射频（RF）电磁（EM）辐射对卫星站操作员在24小时轮班期间应激激素排泄率的影响。对12名在电视通信和空间研究卫星站工作的男性操作员进行了24小时轮班研究。对暴露情况进行了剂量学评估，结果显示为低水平暴露，比吸收率为0.1127 J.kg-1。还对12名未暴露的男性操作员组成的对照组进行了研究，他们具有相似的工作任务和相同的轮班制度。在24小时轮班期间，每隔3小时采用荧光分光光度法对11-氧皮质类固醇（11-OCS）、肾上腺素和去甲肾上腺素进行检测。通过个体间分析、余弦分析和方差分析（ANOVA）对数据进行分析。在暴露的操作员中发现，11-OCS的24小时排泄量显著增加，其昼夜节律紊乱，表现为中值增加、振幅减小和峰值相位偏移。儿茶酚胺排泄率的变化显著，且两个变量的变异性更大。长期暴露于低水平RF EM辐射会引发明显的应激反应，导致11-OCS昼夜节律改变，儿茶酚胺分泌变异性增加。需要通过确定其重要性和预后相关性来阐明与应激系统观察到的改变相关的潜在健康危害。
