Malhotra N, Srivastava P N
Strahlentherapie. 1975 Sep;150(3):344-9.
Male adult gerbils were irradiated with a whole-body dose of 600 R with gamma-rays. The animals were studied for their hematological response on days, 1, 2, 3, 7, 14, and 28 post irradiation. No significant change was noted in erythrocyte number after irradiation. There was a slight fall in hemoglobin and hematocrit values in the early post-irradiation periods. A transient leukocytosis was observed on day 1 after irradiation followed by a sharp fall on day 2 which continued up to day 3. A recovery in leukocyte value was noted after a week of irradiation. Abnormal leukocytes were noted in the peripheral blood on day 2 after irradiation. The results show that the gerbil is radioresistent and is comparable to the rabbit at this dose-level.
成年雄性沙鼠接受了600伦琴的全身γ射线照射。在照射后的第1、2、3、7、14和28天对这些动物的血液学反应进行了研究。照射后红细胞数量没有显著变化。照射后的早期血红蛋白和血细胞比容值略有下降。照射后第1天观察到短暂的白细胞增多,随后在第2天急剧下降并持续到第3天。照射一周后白细胞值有所恢复。照射后第2天在外周血中发现了异常白细胞。结果表明,沙鼠具有辐射抗性,在这个剂量水平上与兔子相当。