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[肾脏位置变异及其在肾脏肿瘤放射治疗照射计划优化中的影响]

[Variations in kidney location and consequences for the radiotherapy of kidney neoplasms in the optimization of irradiation planning].

作者信息

Voss A C, Wöllgens P, Rey G

出版信息

Strahlentherapie. 1975 Dec;150(6):551-6.

PMID:1209677
Abstract

Related to the discussion of optimal radiotherapy planning for the treatment of intrathoracal and intraabdominal tumors being located near the diaphragm, the question arises all over again, if the tumor or the former tumor-bed really are completely encompassed by treatment fields if the patient's topography has changed during a series of irradiations. Using a therapy simulator, the variations of the situs of kidneys are investigated in 20 patients. Changes of the location, which ought to be considered for radiotherapy treatment planning, are observed while changing from dorsal to abdominal position or due to exspiration and inspiration. Hence, consequences result concerning the precision of irradiation planning especially with regard to the sound kidney to be spared. Altogether, a better adjustment to individual features of the topographical correlations is realized. The accurate encompassment of the target volume and the careful sparing of the sound kidney resulting therefrom are justifying that much time must be spent on irradiation planning.

摘要

关于为治疗位于膈肌附近的胸腔内和腹腔内肿瘤制定最佳放射治疗计划的讨论,再次出现了一个问题:如果在一系列照射过程中患者的身体形态发生了变化,肿瘤或先前的肿瘤床是否真的完全被治疗野所覆盖。使用治疗模拟器,对20例患者肾脏位置的变化进行了研究。在从背部位置变为腹部位置或由于呼气和吸气时,观察到了放射治疗计划中应考虑的位置变化。因此,这对照射计划的精确性产生了影响,尤其是对于需要保护的健康肾脏。总的来说,实现了对地形相关性个体特征的更好调整。准确覆盖靶体积以及由此而来的对健康肾脏的谨慎保护,证明在照射计划上必须花费大量时间是合理的。

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