Musumeci R, Doci R, Gennari L, Petrillo R, Valente M, Veronesi U
Tumori. 1975 Sep-Oct;61(5):465-72. doi: 10.1177/030089167506100506.
From 1963 to 1973, 253 patients with cancer of the sigmoid, rectum and anus underwent diagnostic lymphography at the Istituto Nazionale Tumori of Milan. In 218 patients lymphography was performed as part of the intial diagnostic work-up, while in 35 it was done during the follow up period, after surgery. The accuracy of radio-histological correlation was 95%. This confirms the reliability of diagnostic lymphography and its clinical usefulness. In view of these results, this diagnostic tool is essential in the initial evaluation in patients with carcinoma of the anus, because lymphography was superior (28%) to the clinical inspection (6%) in the evaluation of the inguino-iliac lymph nodes. Lymphography is also useful in rectal cancer since it permits, in case of nodal metastases, selection of a group of patients in whom the therapeutic program should be revised. The exam is useless in cancer of the sigmoid. In the small group of patients who had lymphography in the follow up period, this technique was the only to show, in symptomatic patients, the presence of pelvic and/or para-aortic nodal metastases. Lymphography is also useful in these patients for the evaluation of the results of the radio/chemotherapy on involved nodes.
1963年至1973年期间,253例患有乙状结肠、直肠和肛门癌的患者在米兰国家肿瘤研究所接受了诊断性淋巴造影。218例患者的淋巴造影是初始诊断检查的一部分,而35例患者是在术后随访期间进行的。放射组织学相关性的准确率为95%。这证实了诊断性淋巴造影的可靠性及其临床实用性。鉴于这些结果,这种诊断工具在肛门癌患者的初始评估中至关重要,因为在评估腹股沟-髂淋巴结时,淋巴造影(28%)优于临床检查(6%)。淋巴造影在直肠癌中也很有用,因为在发生淋巴结转移的情况下,它可以筛选出一组需要修改治疗方案的患者。该检查对乙状结肠癌无用。在随访期间接受淋巴造影的一小部分患者中,这项技术是唯一能在有症状的患者中显示盆腔和/或腹主动脉旁淋巴结转移的方法。淋巴造影对这些患者评估受累淋巴结的放疗/化疗结果也很有用。