树突状细胞在神经退行性疾病中的作用。
The role of dendritic cells in neurodegenerative diseases.
作者信息
Iribarren Pablo, Cui You-Hong, Le Yingying, Wang Ji Ming
机构信息
Laboratory of Molecular Immunoregulation, Center for Cancer Research, National Cancer Institute at Frederick, Building 560, Room 31-40, Frederick, MD 21702, USA.
出版信息
Arch Immunol Ther Exp (Warsz). 2002;50(3):187-96.
Dendritic cells (DCs) are the most potent antigen-presenting cells (APCs) involved in the induction of adaptive immune responses. The presence of DCs in the central nervous system (CNS) and the active participation of the immune system in a variety of neurodegenerative diseases have been demonstrated. This review will discuss recent findings pertinent to DCs and other antigen-presenting cells in the CNS in health and disease states.
树突状细胞（DCs）是参与诱导适应性免疫反应的最有效的抗原呈递细胞（APC）。中枢神经系统（CNS）中DCs的存在以及免疫系统在多种神经退行性疾病中的积极参与已得到证实。本综述将讨论与健康和疾病状态下中枢神经系统中的DCs和其他抗原呈递细胞相关的最新研究结果。
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