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Measurement of renal function during drug development.

作者信息

Brater D Craig

机构信息

Indiana University School of Medicine, Indianapolis 46202-5114, USA.

出版信息

Br J Clin Pharmacol. 2002 Jul;54(1):87-95. doi: 10.1046/j.1365-2125.2002.01625.x.

DOI:10.1046/j.1365-2125.2002.01625.x
PMID:12100232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1874392/
Abstract
摘要

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RENAL TUBULAR MECHANISMS FOR EXCRETION OF ORGANIC ACIDS AND BASES.有机酸和碱排泄的肾小管机制
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Urinary excretion by nonionic diffusion.通过非离子扩散进行尿液排泄。
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Non-ionic diffusion and the excretion of weak acids and bases.非离子扩散与弱酸和弱碱的排泄
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Tryptophan glycoconjugate as a novel marker of renal function.
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P-glycoprotein-mediated drug secretion in mouse proximal tubule perfused in vitro.P-糖蛋白介导的药物在体外灌注的小鼠近端小管中的分泌。
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Molecular pharmacology of renal organic anion transporters.肾脏有机阴离子转运体的分子药理学
Am J Physiol Renal Physiol. 2000 Aug;279(2):F216-32. doi: 10.1152/ajprenal.2000.279.2.F216.
7
Stereoselective pharmacokinetics of ketoprofen and ketoprofen glucuronide in end-stage renal disease: evidence for a 'futile cycle' of elimination.酮洛芬及其葡萄糖醛酸苷在终末期肾病中的立体选择性药代动力学:消除“无效循环”的证据
Br J Clin Pharmacol. 1999 Oct;48(4):494-500. doi: 10.1046/j.1365-2125.1999.00046.x.
8
P-glycoprotein system as a determinant of drug interactions: the case of digoxin-verapamil.P-糖蛋白系统作为药物相互作用的决定因素:地高辛-维拉帕米的案例
Pharmacol Res. 1999 Oct;40(4):301-6. doi: 10.1006/phrs.1999.0535.
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Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C.人肾苯丙氨酸羟化酶转运体的克隆:狭窄的底物特异性及蛋白激酶C的调节作用
Am J Physiol. 1999 Feb;276(2):F295-303. doi: 10.1152/ajprenal.1999.276.2.F295.
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Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney.人肾多特异性有机阴离子转运体的分子克隆与功能表达
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