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意大利过敏性鼻炎的患病率及特征

Prevalence and features of allergic rhinitis in Italy.

作者信息

Olivieri M, Verlato G, Corsico A, Lo Cascio V, Bugiani M, Marinoni A, de Marco R

机构信息

Servizio de Medicina del Lavoro, Dipartimento di Medicina e Sanità Pubblica, Università de Verona, Italy.

出版信息

Allergy. 2002 Jul;57(7):600-6. doi: 10.1034/j.1398-9995.2002.23537.x.

Abstract

BACKGROUND

Italian data on the prevalence of allergic rhinitis are sparse and with wide variations, maybe because of different diagnostic criteria and methods of investigation. This study analyzes the information on rhinitis collected in northern Italy through standardized methods within the European Community Respiratory Health Survey.

METHODS

A screening questionnaire was sent by mail to a random sample of the general population aged 20-44 years, and nonresponders were contacted again by phone, achieving a final response rate of 86% (6031/7000). Among the responders, 914 randomly selected underwent a standardized clinical interview, skin prick test (SPT) and total and specific immunoglobulin (Ig)E determination.

RESULTS

The overall prevalence of self-reported allergic rhinitis was 15.9% (95% CI 15.0-16.8%). Allergic rhinitis was more common in men below 35 years and in women older than that (P = 0.006), in urban areas (P < 0.001) and in early responders (P < 0.001). A larger percentage of subjects (37.7%) reported nasal symptoms when exposed to indoor or outdoor allergens. Atopy was present in 79% of the subjects reporting allergic rhinitis.

CONCLUSIONS

This study demonstrates that the prevalence of allergic rhinitis in northern Italy is similar to the prevalence observed in other European countries and that this disease is more common in urban areas.

摘要

背景

意大利关于变应性鼻炎患病率的数据稀少且差异很大,这可能是由于不同的诊断标准和调查方法所致。本研究分析了在欧洲共同体呼吸健康调查中通过标准化方法在意大利北部收集的鼻炎信息。

方法

通过邮件向年龄在20 - 44岁的普通人群随机样本发送筛查问卷,对未回复者再次进行电话联系,最终回复率为86%(6031/7000)。在回复者中,随机选取914人进行标准化临床访谈、皮肤点刺试验(SPT)以及总免疫球蛋白和特异性免疫球蛋白(Ig)E测定。

结果

自我报告的变应性鼻炎总体患病率为15.9%(95%可信区间15.0 - 16.8%)。变应性鼻炎在35岁以下男性和35岁以上女性中更常见(P = 0.006),在城市地区更常见(P < 0.001),在早期回复者中更常见(P < 0.001)。更大比例的受试者(37.7%)报告在接触室内或室外过敏原时出现鼻部症状。在报告有变应性鼻炎的受试者中,79%存在特应性。

结论

本研究表明,意大利北部变应性鼻炎的患病率与其他欧洲国家观察到的患病率相似,且该疾病在城市地区更为常见。

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