Daskalakis G J, Nicolaides K H
Harris Birthright Research Center For Fetal Medicine, Kings College Hospital Medical School, London, UK.
Ultrasound Obstet Gynecol. 2002 Jul;20(1):79-81. doi: 10.1046/j.1469-0705.2002.00631.x.
We report on two cases of monozygotic twins discordant for body stalk anomaly, diagnosed prenatally in a multicenter ultrasound screening study at 10-14 weeks of gestation. Ultrasound showed a large abdominal wall defect with most of the abdominal contents and almost half of the body in the celomic cavity, in association with severe kyphoscoliosis and a very short umbilical cord. Both pregnancies were managed expectantly and delivered by Cesarean section. The abnormal babies died soon after birth and autopsy confirmed the sonographic diagnosis. Body stalk anomaly in twins is extremely rare. These are, to our knowledge, the first cases reported on monozygotic twins discordant for this anomaly, indicating that the incomplete twinning theory cannot uniformly explain the pathogenesis of the body stalk in twins.
我们报告了两例单卵双胞胎出现身体茎干异常的病例，这是在一项多中心超声筛查研究中于妊娠10至14周时产前诊断出来的。超声显示存在一个大的腹壁缺损，大部分腹腔内容物以及近半个身体位于体腔中，同时伴有严重的脊柱侧凸和极短的脐带。两次妊娠均采取期待治疗，并通过剖宫产分娩。异常婴儿出生后不久死亡，尸检证实了超声诊断结果。双胞胎中的身体茎干异常极为罕见。据我们所知，这是首次报道的单卵双胞胎出现这种异常的病例，表明不完全双胎理论不能统一解释双胞胎中身体茎干的发病机制。
