Lai I-Rue, Lee Wei-Jei, Huang Ming-Te
Department of Surgery, National Taiwan University Hospital, 399 Fuhsing Road, San-shia Town, Taipei, Hsien 237, Taiwan.
J Formos Med Assoc. 2002 May;101(5):332-6.
Laparoscopic Heller cardiomyotomy for the treatment of achalasia can be performed safely. The application of this minimally invasive approach has not been reported in Taiwan. This study assessed the results obtained using this new method in Taiwanese patients.
From January 1998 to December 2000, we recruited 10 patients (3 men, 7 women; average age 37.3 yr) with achalasia who underwent laparoscopic cardiomyotomy and fundoplication. Before and after surgery, the severity of three symptoms (dysphagia, regurgitation, chest pain) was evaluated by symptom scores (0 = symptom absent; 1 = occasional; 2 = every day; 3 = every meal). Barium swallow study and panendoscopy were performed in all patients. Esophageal manometry was performed before surgery in seven patients. Laparoscopic Heller myotomy and anterior (Dor) fundoplication was performed through five abdominal trocar sites. The myotomy extended 7 cm, 6 cm above and 1 cm below the gastroesophageal junction.
Barium swallow study showed that one patient had a normal or mildly dilated esophagus (< 3 cm) and nine patients had moderate esophageal dilatation (3-7 cm). Mean operative time was 162.5 +/- 29.7 minutes. Mean hospital stay was 5.1 +/- 1.6 days (range, 3-9 d). The mean follow-up time was 21.3 +/- 9.4 months, longer than 19 months in eight patients. Dysphagia was alleviated in all but one patient (90%). Regurgitation and chest pain also improved in all patients. No intraoperative complication occurred. Postoperative weight gain (> 4 kg) was noted in all patients.
Laparoscopic Heller myotomy and anterior fundoplication result in significant symptomatic relief for patients with achalasia.
腹腔镜下贲门肌层切开术治疗贲门失弛缓症可安全进行。台湾地区尚未报道过这种微创方法的应用。本研究评估了在台湾患者中使用这种新方法所取得的结果。
1998年1月至2000年12月,我们招募了10例贲门失弛缓症患者(3例男性,7例女性;平均年龄37.3岁),他们接受了腹腔镜贲门肌层切开术和胃底折叠术。手术前后,通过症状评分(0 = 无症状;1 = 偶尔出现;2 = 每天出现;3 = 每餐出现)评估三种症状(吞咽困难、反流、胸痛)的严重程度。所有患者均进行了吞钡检查和全内镜检查。7例患者在手术前进行了食管测压。通过五个腹部穿刺部位进行腹腔镜贲门肌层切开术和前位(Dor)胃底折叠术。肌层切开术在胃食管交界处上方6 cm和下方1 cm处延伸7 cm。
吞钡检查显示,1例患者食管正常或轻度扩张(< 3 cm),9例患者食管中度扩张(3 - 7 cm)。平均手术时间为162.5 ± 29.7分钟。平均住院时间为5.1 ± 1.6天(范围3 - 9天)。平均随访时间为21.3 ± 9.4个月,8例患者随访时间超过19个月。除1例患者外,所有患者的吞咽困难均得到缓解(90%)。所有患者的反流和胸痛也有所改善。术中无并发症发生。所有患者术后体重均增加(> 4 kg)。
腹腔镜贲门肌层切开术和前位胃底折叠术可使贲门失弛缓症患者的症状得到显著缓解。