Yuasa S, Suwa A, Hirakata M, Hibi N, Iwao Y, Koizumi K, Mimori T, Ikeda Y
Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Clin Exp Rheumatol. 2002 May-Jun;20(3):407-10.
Gastrointestinal involvement is often seen in patients with systemic lupus erythematosus (SLE). All parts of the gastrointestinal tract may be affected. However, rectal involvement at onset is rare. We describe here a case of SLE in which rectal ulcers due to vasculitis occurred as the initial manifestation of the disease without involvement of any other organ. The ulcers worsened, along with the appearance of lupus nephritis 5 years later When steroid therapy was initiated, there was rapid clinical and radiographic improvement. Our case suggests that rectal ulcer is a rare but important complication of SLE and can represent the initial and sole clinical manifestation of the disease.
胃肠道受累在系统性红斑狼疮（SLE）患者中较为常见。胃肠道的各个部位都可能受到影响。然而，发病时直肠受累较为罕见。我们在此描述一例SLE病例，其中血管炎导致的直肠溃疡是该疾病的首发表现，且无其他器官受累。5年后，随着狼疮性肾炎的出现，溃疡病情加重。开始使用类固醇治疗后，临床和影像学表现迅速改善。我们的病例表明，直肠溃疡是SLE一种罕见但重要的并发症，可作为该疾病的初始且唯一临床表现。
