Popova E N, Krivitskaia G N
Zh Nevropatol Psikhiatr Im S S Korsakova. 1975;75(7):1064-9.
The authors have shown similarities of structural changes in the neuron and interneuronal relations found in the brains of rats under indopan and LSD stimulation of the CNS with certain differences in the localization of the changes in the functionally different brain systems. A high sensitivity of the sensory-motor cortex and the subcortical formations of the brain, rich in dopamine and serotonin, to indopan has been marked. LSD central effects were conditioned by the influence of the drug not only on the synapsis, but on the cell body components of the different brain systems, especially in the visual. The observed changes were allocated to categories of functional disturbances.
作者已经表明,在中枢神经系统受到吲哚泮和麦角酸二乙酰胺(LSD)刺激的大鼠大脑中,所发现的神经元结构变化以及神经元间关系存在相似性,不过在功能不同的脑系统中,这些变化的定位存在某些差异。已经注意到,富含多巴胺和血清素的感觉运动皮层及大脑皮层下结构对吲哚泮具有高度敏感性。LSD的中枢效应不仅取决于该药物对突触的影响,还取决于其对不同脑系统细胞体成分的影响,尤其是在视觉系统中。观察到的变化被归类为功能障碍。