Kariuki Samuel, Revathi Gunturu, Gakuya Francis, Yamo Victor, Muyodi Jane, Hart C Anthony
Centre for Microbiology Research, Kenya Medical Research Institute, P.O. Box 43640, Nairobi, Kenya.
FEMS Immunol Med Microbiol. 2002 Jul 12;33(3):165-71. doi: 10.1111/j.1574-695X.2002.tb00587.x.
Antibiogram patterns and chromosomal DNA typing were used to compare 151 non-typhoidal Salmonella spp. (NTS) isolated from patients and 78 from animals, environmental or food specimens obtained within or near the homes of patients with invasive salmonellosis. The majority of NTS from humans (137; 90.7%) were Salmonella enterica serotype Typhimurium (S. Typhimurium) and S. Enteritidis. Chicken specimens and feeds produced (24; 52.2%) S. Enteritidis, while S. Agona was the predominant (20; 77%) serovar among pigs and dairy cows. The majority (97; 64.2%) of NTS from humans were multidrug resistant, while NTS from cows, pigs, beef carcass swabs and sewers were fully susceptible to all antibiotics tested. Pulsed-field gel electrophoresis patterns of XbaI-digested genomic DNA of NTS from the humans and the chickens were different. However, S. Enteritidis from chickens, and S. Braenderup and S. Agona from cows and pigs were clustered together in one group. There was no significant relatedness between NTS isolates from humans and those from animals, food or the environment in close contact to humans.
采用抗生素敏感性模式和染色体DNA分型方法，对从患者体内分离出的151株非伤寒沙门氏菌（NTS）以及从动物、环境或患者家中或附近获取的食品标本中分离出的78株NTS进行比较。来自人类的大多数NTS（137株；90.7%）为肠炎沙门氏菌鼠伤寒血清型（鼠伤寒沙门氏菌）和肠炎沙门氏菌。鸡标本和饲料中产肠炎沙门氏菌的比例为24株（52.2%），而阿哥纳沙门氏菌是猪和奶牛中占主导地位的血清型（20株；77%）。来自人类的大多数NTS（97株；64.2%）对多种药物耐药，而来自奶牛、猪、牛胴体拭子和下水道的NTS对所有测试抗生素均完全敏感。来自人类和鸡的NTS经XbaI酶切的基因组DNA的脉冲场凝胶电泳图谱不同。然而，来自鸡的肠炎沙门氏菌以及来自奶牛和猪的布伦德鲁普沙门氏菌和阿哥纳沙门氏菌聚集在一组。来自人类的NTS分离株与来自动物、食品或与人类密切接触的环境中的分离株之间没有显著相关性。
