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疼痛性皮肤病变、肾衰竭与急诊甲状旁腺切除术

Painful cutaneous lesions, renal failure and urgent parathyroidectomy.

作者信息

Younis Naveed, Sells Robert A, Desmond Anthony, Helliwell Timothy, Guerin Deirdre, Jibani Mahdi, Vora Jiten

机构信息

Department of Medicine, Royal Liverpool University Hospital, UK.

出版信息

J Nephrol. 2002 May-Jun;15(3):324-9.

Abstract

We describe two patients with end stage renal failure who presented with painful skin lesions, which rapidly progressed to become necrotic and gangrenous. The diagnosis was calciphylaxis, a rare disorder due to calcification and luminal fibrosis of small and medium sized cutaneous and systemic vessels. Both patients had tertiary hyperparathyroidism. An urgent parathyroidectomy was performed on one patient, which relieved her symptoms; the other required local surgery but refused parathyroidectomy and died.

摘要

我们描述了两名终末期肾衰竭患者,他们出现了疼痛性皮肤病变,这些病变迅速发展为坏死和坏疽。诊断为钙化防御,这是一种由于中小尺寸皮肤和全身血管钙化及管腔纤维化引起的罕见疾病。两名患者均患有三发性甲状旁腺功能亢进症。其中一名患者接受了紧急甲状旁腺切除术,症状得到缓解;另一名患者需要进行局部手术,但拒绝甲状旁腺切除术,最终死亡。

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