Jung K, Neumann R, Liese W, Egger E
J Clin Chem Clin Biochem. 1979 Nov;17(11):717-9. doi: 10.1515/cclm.1979.17.11.717.
EDTA and EGTA, added to the reaction mixture for the activity determination of creatine kinase, stimulate the activity of creatine kinase to various extents by suppressing the inhibitory effect of Ca2+ ions. The activation effect is highest for isoenzyme BB, less for isoenzyme MB, and lowest for isoenzyme MM.
在用于肌酸激酶活性测定的反应混合物中添加的乙二胺四乙酸(EDTA)和乙二醇双(2-氨基乙基醚)四乙酸(EGTA),通过抑制Ca2+离子的抑制作用,在不同程度上刺激肌酸激酶的活性。对同工酶BB的激活作用最高,对同工酶MB的激活作用较小,对同工酶MM的激活作用最低。