Jung K, Neumann R, Liese W, Egger E
J Clin Chem Clin Biochem. 1979 Nov;17(11):717-9. doi: 10.1515/cclm.1979.17.11.717.
EDTA and EGTA, added to the reaction mixture for the activity determination of creatine kinase, stimulate the activity of creatine kinase to various extents by suppressing the inhibitory effect of Ca2+ ions. The activation effect is highest for isoenzyme BB, less for isoenzyme MB, and lowest for isoenzyme MM.