Murashova N S, Golosova T V, Gerasimova L I, Gorbuntsova R V, Ivanova N P
Antibiotiki. 1975 Apr;20(4):369-73.
Examination of 108 patients showed that burn disease was accompanied by significant impairments in the host natural resistance. Inclusion of intramuscular administrations of crystalline lysozyme into the complex therapy of such patients during septicotoxemia provided an increase in the factors of humoral and cell immunity. In most of the cases the dynamics of the indices of the host immunological reactivity correlated with the character of the clinical signs of the burn disease. The positive effect of lysozyme was evident in the cases with severe complications such as pneumonia, bacteriemia and burns of the upper respiratory organs.
对108例患者的检查表明,烧伤疾病伴有宿主自然抵抗力的显著损害。在败血症毒血症期间,将结晶溶菌酶肌肉注射纳入此类患者的综合治疗中,可提高体液免疫和细胞免疫因子。在大多数情况下,宿主免疫反应性指标的动态变化与烧伤疾病临床症状的特征相关。溶菌酶的积极作用在伴有严重并发症如肺炎、菌血症和上呼吸道器官烧伤的病例中很明显。