Schraffordt Koops H, Oldhoff J, van der Ploeg E, Vermey A, Eibergen R
Arch Chir Neerl. 1975;27(4):237-43.
The authors present a survey of changed views on the treatment of patients with malignant melanoma of the extremities. In addition to conventional therapy, regional perfusion is discussed. Over the period 1964-1970, 115 perfusions were performed in 75 patients. The perfusions were confined to patients with a tumor infiltrating beyond the stratum papillare. The 4-year survival of 30 patients with a primary tumor, without demonstrable metastases at the moment of perfusion, was found to be 77%. The percentage of local recurrences was significantly lower after perfusion than after conventional surgery.
作者介绍了对四肢恶性黑色素瘤患者治疗观点的变化调查。除了传统疗法外，还讨论了区域灌注。在1964年至1970年期间，对75名患者进行了115次灌注。灌注仅限于肿瘤浸润超出乳头层的患者。发现30例原发性肿瘤患者在灌注时无明显转移，其4年生存率为77%。灌注后局部复发的百分比明显低于传统手术后。
