Rhebergen G A, Schölzel-Dorenbos C J M
Polikliniek geriatrie, Slingeland Ziekenhuis Kruisbergseweg 25, 7009 BL Doetinchem.
Tijdschr Gerontol Geriatr. 2002 Jun;33(3):119-23.
The aim of this study was to determine the prevalence of orthostatic (OH) and postprandial hypotension (PPH) in Dutch elderly patients admitted to a medical ward and to explore patient characteristics associated with OH and PPH: symptoms, medications and comorbidity. We studied 50 patients, mean age 78.8 years, 68% female. Orthostatic hypotension (OH) was defined as a decrease of systolic blood pressure (BP) > or = 20 or diastolic > or = 10 mm Hg after 3 minutes of standing. To diagnose postprandial hypotension (PPH) BP was measured sitting before and 30 minutes after the start of patient's noon meal, the same criteria were applied. We registered changes in BP, pulse rate, complaints, reason for hospitalization, medication and comorbidity: hypertension, diabetes mellitus and Parkinson(ism). We found OH in 24% of the patients, PPH was diagnosed more frequently: in 34%. 10% had both, but there were no relations between OH and PPH. In none of the patients OH and PPH were measured before our assessment. Pulse rate increased respectively 8 and 3/min. With OH and PPH. Both subjective and objective complaints were significantly associated with OH, where as only subjective non-specific complaints were associated with PPH. Objective complaints were very rare in PPH. OH and PPH were not significantly associated with medication use and comorbidity. PPH and OH are common in hospitalized elderly patients. OH is more often symptomatic than PPH. We found no relationship with medication use or comorbidity. According to research literature, however, OH and PPH are associated with higher morbidity, mortality and possibly cognitive decline. Therapeutic measures must be considered, especially in the presence of comorbidity such as significant carotid artery occlusion.
本研究的目的是确定入住内科病房的荷兰老年患者中体位性低血压(OH)和餐后低血压(PPH)的患病率,并探讨与OH和PPH相关的患者特征:症状、药物治疗和合并症。我们研究了50例患者,平均年龄78.8岁,68%为女性。体位性低血压(OH)定义为站立3分钟后收缩压(BP)下降≥20 mmHg或舒张压下降≥10 mmHg。为诊断餐后低血压(PPH),在患者午餐开始前坐位测量血压,并在开始后30分钟测量,采用相同标准。我们记录了血压、脉搏率、主诉、住院原因、药物治疗和合并症的变化:高血压、糖尿病和帕金森病。我们发现24%的患者有OH,PPH的诊断更为频繁:34%。10%的患者两者都有,但OH和PPH之间没有关联。在我们评估之前,没有患者测量过OH和PPH。脉搏率分别增加8次/分钟和3次/分钟,分别与OH和PPH相关。主观和客观主诉均与OH显著相关,而只有主观非特异性主诉与PPH相关。PPH中客观主诉非常罕见。OH和PPH与药物使用和合并症无显著关联。PPH和OH在住院老年患者中很常见。OH比PPH更常出现症状。我们未发现与药物使用或合并症有关。然而,根据研究文献,OH和PPH与更高的发病率、死亡率以及可能的认知功能下降有关。必须考虑采取治疗措施,尤其是在存在严重颈动脉闭塞等合并症的情况下。