纤维肌痛的合理且有针对性的药物治疗。

Rational and targeted pharmacologic treatment of fibromyalgia.

作者信息

Barkhuizen André

机构信息

Department of Medicine, Oregon Health and Science University, Portland VA Medical Center, Portland, OR, USA.

出版信息

Rheum Dis Clin North Am. 2002 May;28(2):261-90. doi: 10.1016/s0889-857x(01)00011-4.

DOI:10.1016/s0889-857x(01)00011-4

PMID:12122917

Abstract

Despite disappointing results when subjected to randomized clinical trials, pharmacologic agents remain an important component of FM management. Addressing the main symptoms of pain, disturbed sleep, mood disturbances, fatigue, and associated conditions is essential to improve patient functioning and enhanced quality of life. However, much work remains to design clinical trials which address the complexity of FM, while satisfying evidence based medicine paradigms.

摘要

尽管在随机临床试验中结果令人失望，但药物制剂仍是纤维肌痛管理的重要组成部分。解决疼痛、睡眠障碍、情绪紊乱、疲劳及相关病症等主要症状对于改善患者功能和提高生活质量至关重要。然而，在设计既能应对纤维肌痛复杂性又符合循证医学范式的临床试验方面，仍有许多工作要做。