26-降-25-异丙基-麦角甾-5,7,22E-三烯-3β-醇：一种从牙买加海绵Agelas sceptrum中分离得到的新型C(29)甾醇。

26-Nor-25-isopropyl-ergosta-5,7,22E-trien-3beta-ol: a new C(29) sterol from the sponge Agelas sceptrum from Jamaica.

作者信息

Hu Jin-Feng, Kelly Michelle, Hamann Mark T

机构信息

Department of Pharmacognosy and National Center for the Development of Natural Products, School of Pharmacy, The University of Mississippi, P.O. Box 1848, University, MS 38677, USA.

出版信息

Steroids. 2002 Aug;67(9):743-7. doi: 10.1016/s0039-128x(02)00033-8.

DOI:10.1016/s0039-128x(02)00033-8

PMID:12123785

Abstract

In addition to several known sterols, a new C(29) marine sterol with a normal ergosterol nucleus but a modified side chain, named 26-nor-25-isopropyl-ergosta-5,7,22E-trien-3beta-ol, was isolated from the Jamaican sponge Agelas sceptrum. The structures were assigned by spectroscopic methods including high-resolution 2D NMR techniques.

摘要

除了几种已知的甾醇外，还从牙买加海绵Agelas sceptrum中分离出一种新的C(29)海洋甾醇，其具有正常的麦角甾醇核但侧链经过修饰，命名为26-降-25-异丙基-麦角甾-5,7,22E-三烯-3β-醇。通过包括高分辨率二维核磁共振技术在内的光谱方法确定了其结构。