Myc——这是来自地狱的癌基因吗？
Myc-Is this the oncogene from Hell?
作者信息
Soucek Laura, Evan Gerard
机构信息
Cancer Research Institute, University of California, San Francisco, Cancer Center, 2340 Sutter Street, 94143, USA.
出版信息
Cancer Cell. 2002 Jun;1(5):406-8. doi: 10.1016/s1535-6108(02)00077-6.
Abstract
A new paper implicates the Myc oncoprotein in the direct induction of DNA damage and consequent genome instability in cultured cells. However, it is less clear whether Myc induces the same genetic pandemonium in vivo.
摘要
一篇新论文表明，原癌基因Myc蛋白可直接诱导培养细胞中的DNA损伤及随后的基因组不稳定。然而，Myc在体内是否会引发同样的基因混乱尚不清楚。
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