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与巨大孤立性胸膜纤维瘤相关的严重低血糖症。

Severe hypoglycaemia associated with a giant solitary fibrous tumor of the pleura.

作者信息

Filosso P L, Oliaro A, Rena O, Papalia E, Ruffini E, Mancuso M

机构信息

Department of Thoracic Surgery, University of Torino, San Giovanni Battista Hospital, Italy.

出版信息

J Cardiovasc Surg (Torino). 2002 Aug;43(4):559-61.

Abstract

Solitary fibrous tumors (SFT) of the pleura are a rare neoplasm, with benign biological behaviour. Recurrences are rare, and no distant metastases are described in the literature. SFT can secrete hormone-like substances, responsible for paraneoplastic syndromes. The authors describe a case of severe hypoglycaemia due to insulin-like growth factor II (IGF-2)'s secretion by a giant SFT of the pleura. Hypoglycaemia was controlled by the resection of the tumor. Diagnosis and surgical management of these neoplasms are also discussed.

摘要

胸膜孤立性纤维瘤(SFT)是一种罕见的肿瘤,具有良性生物学行为。复发罕见,文献中未描述有远处转移。SFT可分泌类似激素的物质,导致副肿瘤综合征。作者描述了一例因胸膜巨大SFT分泌胰岛素样生长因子II(IGF-2)而导致严重低血糖的病例。通过切除肿瘤控制了低血糖。还讨论了这些肿瘤的诊断和手术管理。

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