Sakamoto T, Kaneshige H, Takeshi A, Tsushima T, Hasegawa S
Division of Pulmonary Medicine, University of Tsukuba, Ibaraki, Japan.
Chest. 1994 Sep;106(3):965-7. doi: 10.1378/chest.106.3.965.
Recurrent hypoglycemia occurred in a 48-year-old woman with a localized pleural mesothelioma. During hypoglycemia, serum high molecular weight insulin-like growth factor II (IGF-II) was elevated. The tumor also contained a high level of high molecular weight IGF-II. We propose that the primary cause of the hypoglycemia in this patient was the high molecular weight IGF-II produced by the tumor.
一名48岁患有局限性胸膜间皮瘤的女性出现复发性低血糖。在低血糖期间,血清高分子量胰岛素样生长因子II(IGF-II)升高。肿瘤中也含有高水平的高分子量IGF-II。我们认为该患者低血糖的主要原因是肿瘤产生的高分子量IGF-II。