Chanda Amitabha, Nanda Anil
Department of Neurosurgery, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130-3932, USA.
Surg Neurol. 2002 May;57(5):340-4; discussion 334-5. doi: 10.1016/s0090-3019(02)00686-9.
Cavernomas are rare vascular lesions of the brain that can bleed. However, the risk of bleeding is lower than that of aneurysms or arteriovenous malformations. In selected cases, bleeding cavernomas require surgical management. Presented here is a case of multiple cavernomas of the brain with simultaneous bleeding in two different lesions, along with its management. Although multiple cavernomas have been described in the literature, simultaneous bleeding in two different lesions is rare.
A 52-year-old woman presented with difficulty maintaining balance, double vision, and slurred speech. She had had multiple surgeries for cavernous angioma of the brain in the past. Examination and investigations revealed two cavernomas, one in the dorsal midbrain region and one in the left occipital region. Her clinical condition deteriorated suddenly, and further evaluation revealed bleeding in both the cavernomas. The lesion in the midbrain was removed surgically. Since the lesion was in the posterior midbrain, a posterior interhemispheric approach was used with the help of frameless stereotactic navigation. Total excision was achieved. The lesion in the occipital lobe was not operated on. The patient had an uneventful recovery. It was planned to observe the progress of the occipital cavernoma by serial magnetic resonance imaging scans.
Although there may be simultaneous bleeding in two or even more lesions, surgical treatment should be undertaken for the lesions jeopardizing critical structures or exerting mass effects. Additionally, it was discovered that frameless stereotactic navigation was of immense help in delineating the lesion and for safe excision of the lesion in critical areas.
海绵状血管瘤是罕见的可出血的脑部血管病变。然而,其出血风险低于动脉瘤或动静脉畸形。在某些特定情况下,出血性海绵状血管瘤需要手术治疗。本文介绍了一例脑部多发海绵状血管瘤,两个不同病灶同时出血的病例及其治疗情况。虽然文献中已有关于多发海绵状血管瘤的描述,但两个不同病灶同时出血的情况较为罕见。
一名52岁女性出现平衡维持困难、复视和言语含糊不清的症状。她过去曾因脑部海绵状血管瘤接受过多次手术。检查和调查发现两个海绵状血管瘤,一个位于中脑背侧区域,另一个位于左枕叶区域。她的临床状况突然恶化,进一步评估显示两个海绵状血管瘤均有出血。中脑的病灶通过手术切除。由于病灶位于中脑后部,在无框架立体定向导航的帮助下采用了后半球间入路。实现了全切。枕叶的病灶未进行手术。患者恢复顺利。计划通过系列磁共振成像扫描观察枕叶海绵状血管瘤的进展情况。
尽管可能有两个甚至更多病灶同时出血,但对于危及关键结构或产生占位效应的病灶应进行手术治疗。此外,发现无框架立体定向导航在勾勒病灶以及安全切除关键区域的病灶方面有极大帮助。