Hirota Masahiko, Kimura Yu, Ishiko Takatoshi, Beppu Toru, Yamashita Yasuyuki, Ogawa Michio
Departments of Surgery II, Kumamoto University Medical School, Kumamoto, Japan.
Pancreas. 2002 Jul;25(1):63-7. doi: 10.1097/00006676-200207000-00015.
Contrast-enhanced computed tomography (CT) is the gold standard for assessing the severity of acute pancreatitis, especially for evaluating the presence of pancreatic necrosis (poorly perfused area). However, the contrast medium used for CT is potentially toxic to the pancreas and kidney. Therefore, medical institutions without facilities for hemodialysis hesitate to acquire contrast-enhanced CT images. Diagnostic values of magnetic resonance imaging (MRI) in pancreatic diseases have been shown.
To evaluate the usefulness of MRI in the assessment of the severity of acute pancreatitis.
All necrotic regions in the pancreas were visualized by gadolinium-enhanced MRI. Furthermore, MRI can discriminate the poorly perfused pancreatic area, namely so-called "pancreatic necrosis" judged on CT, into three parts: 1) necrotic area of the pancreatic parenchyma, 2) perinecrotic fluid collection, and 3) hemorrhagic foci. Inflammatory changes that were required for severity grading were also evaluated sufficiently by MRI.
These results suggest that MRI is useful for the assessment of severity of acute pancreatitis.
增强计算机断层扫描(CT)是评估急性胰腺炎严重程度的金标准,尤其用于评估胰腺坏死(灌注不良区域)的存在情况。然而,用于CT的造影剂对胰腺和肾脏具有潜在毒性。因此,没有血液透析设备的医疗机构在获取增强CT图像时会有所顾虑。磁共振成像(MRI)在胰腺疾病中的诊断价值已得到证实。
评估MRI在评估急性胰腺炎严重程度方面的实用性。
钆增强MRI可显示胰腺内所有坏死区域。此外,MRI能够将CT上判断为灌注不良的胰腺区域,即所谓的“胰腺坏死”,分为三个部分:1)胰腺实质坏死区域,2)坏死周围液体聚集,3)出血灶。MRI也能充分评估严重程度分级所需的炎症变化。
这些结果表明,MRI对评估急性胰腺炎的严重程度有用。