Nasser José Augusto, Falavigna Asdrubal, Alaminos Armando, Bonatelli Antônio de Pádua, Ferraz Fernando
Serviço de Neurocirurgia, Hospital Pró-Cardíaco, Rio de Janeiro, Brasil.
Arq Neuropsiquiatr. 2002 Jun;60(2-B):429-34.
We present our results in 4 patients with tremor, in whom electrodes (uni and bilateral) for Deep Brain Stimulation (DBS) were implanted in the ventral intermediate nucleus (VIM) of the thalamus.
Four patients with disabling tremor, with drug-resistant spite of optimum therapeutic trials with poor response were referred to do surgery. Two patients had bilateral essential tremor. These patients were implanted with electrodes for DBS 3387 (Medtronic). Two patients had unilateral parkinsonian tremor and they received unilateral implantation of model 3387 DBS.
All four patients showed relieve of the tremor symptoms with significant tremor control seen at the scores. There were no definite adverse events after the electrodes implants for DBS; adverse events were transient and promptly reversed after the adjustment of the parameters.
The results the authors found in this study indicate that VIM-stimulation is effective for tremor control either parkinsonian or essential tremor. The results correlate with the data in the literature.
我们展示了4例震颤患者的治疗结果，这些患者接受了丘脑腹中间核（VIM）的深部脑刺激（DBS）电极植入（单侧和双侧）。
4例致残性震颤患者，尽管经过最佳治疗试验且反应不佳，但对药物仍有抵抗，被转诊接受手术。2例患者患有双侧特发性震颤。这些患者植入了美敦力3387型DBS电极。2例患者患有单侧帕金森震颤，他们接受了单侧3387型DBS植入。
所有4例患者的震颤症状均得到缓解，评分显示震颤得到显著控制。DBS电极植入后没有明确的不良事件；不良事件是短暂的，在参数调整后迅速逆转。
作者在本研究中发现的结果表明，VIM刺激对帕金森震颤或特发性震颤的震颤控制有效。结果与文献数据相关。
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