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[动脉粥样硬化、酒精与糖尿病]

[Atherosclerosis, alcohol and diabetes].

作者信息

Bartos V

机构信息

Centrum diabetologie Institutu klinické a experimentální medicíny, Praha.

出版信息

Vnitr Lek. 2002 Jun;48(6):529-33.

Abstract

Diabetes is a known risk factor of atherosclerosis, moderate consumption of alcohol was reported to reduce the cardiovascular morbidity and mortality. This review presents information on the possible mechanisms of the antiatherogenic effect of alcohol and data of the effect of moderate alcohol drinking on the prevention of cardiovascular diseases. Red wine contains polyphenols with an antioxidant effect, alcohol is metabolized to acetaldehyde which was proved to inhibit the formation of advanced glycation endproducts (AGE) and lipoprotein oxidation. Diabetic patients may benefit from moderate consumption of alcohol beverages only if the risk of hypoglycemia is safely excluded.

摘要

糖尿病是动脉粥样硬化的已知危险因素,据报道适度饮酒可降低心血管发病率和死亡率。本综述介绍了酒精抗动脉粥样硬化作用的可能机制以及适度饮酒对预防心血管疾病影响的数据。红酒含有具有抗氧化作用的多酚,酒精代谢为乙醛,已证明乙醛可抑制晚期糖基化终产物(AGE)的形成和脂蛋白氧化。仅当低血糖风险被安全排除时,糖尿病患者才可能从适度饮用酒精饮料中获益。

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