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[痤疮丙酸杆菌所致术后硬脑膜下积脓]

[Postoperative subdural empyema due to Propionibacterium acnes].

作者信息

Uozumi Youichi, Nawashiro Hiroshi, Higo Reiko, Otani Naoki, Fukui Shinji, Suzuki Takamoto, Ishihara Shoichiro, Katoh Hiroshi, Tsuzuki Nobusuke, Miyazawa Takahito, Shima Katsuji, Tokumaru Aya, Aida Shinsuke

机构信息

Department of Neurosurgery, National Defense Medical College, 3-2 Namiki, Tokorozawa-city, Saitama 359-8513, Japan.

出版信息

No Shinkei Geka. 2002 Jul;30(7):731-3.

Abstract

Propionibacterium acnes are gram-positive pleomorphic rods that grow under an anaerobic condition. They are the most frequent inhabitants of sebaceous glands of skin, hair follicles, mouth, upper respiratory tract, and as a frequent contaminant in laboratory cultures. Propionibacterium acnes is an underestimated but significant cause of postneurosurgical infection, especially in the presence of foreign bodies such as shunt systems. We present a rare case with a postoperative subdural empyema in which the only pathogen isolated was Propionibacterium acnes. In our case, the clinical course was atypically rapid. The most effective antibiotic therapy for Propionibacterium acnes infections has not been established. However, high dose penicillin in combination with surgical drainage and removal of foreign bodies is recommended as the treatment of choice.

摘要

痤疮丙酸杆菌是革兰氏阳性多形性杆菌,在厌氧条件下生长。它们是皮肤皮脂腺、毛囊、口腔、上呼吸道最常见的寄居菌,也是实验室培养中常见的污染物。痤疮丙酸杆菌是神经外科术后感染的一个被低估但重要的病因,尤其是在存在分流系统等异物的情况下。我们报告一例罕见的术后硬膜下积脓病例,其中分离出的唯一病原体是痤疮丙酸杆菌。在我们的病例中,临床病程异常迅速。针对痤疮丙酸杆菌感染最有效的抗生素治疗方法尚未确定。然而,推荐大剂量青霉素联合手术引流和清除异物作为首选治疗方法。

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