Traub Stephen J, Hoffman Robert S, Nelson Lewis S
New York City Poison Control Center, NY, USA.
Vet Hum Toxicol. 2002 Aug;44(4):235-9.
Chlorine gas exposure is uncommon in children and when it occurs usually results in mild ocular, oropharyngeal, or respiratory symptoms. Occasionally, however, chlorine gas poisoning may cause severe pulmonay toxicity. We report the case of a 14-y-old boy with a history of asthma who was exposed to chlorine gas as a result of an ill-advised science experiment. His clinical condition deteriorated over the course of several hours, and he required intubation and ventilatory support. During his hospitalization, he developed the acute respiratory distress syndrome. He was treated with positive pressure ventilation, beta-adrenergic agonists, and corticosteroids. After 19 d, he was extubated and subsequently made an excellent recovery. We discuss his case and review the etiology, pathophysiology, clinical presentation, laboratory findings, treatment and possible long-term sequelae of chlorine gas toxicity.
儿童接触氯气的情况并不常见,一旦发生,通常会导致轻微的眼部、口咽部或呼吸道症状。然而,偶尔氯气中毒可能会引起严重的肺部毒性。我们报告一例14岁有哮喘病史的男孩,因一次欠考虑的科学实验而接触氯气。他的临床状况在数小时内恶化,需要插管和通气支持。住院期间,他发展为急性呼吸窘迫综合征。给予他正压通气、β肾上腺素能激动剂和皮质类固醇治疗。19天后,他拔管,随后恢复良好。我们讨论他的病例,并回顾氯气中毒的病因、病理生理学、临床表现、实验室检查结果、治疗及可能的长期后遗症。