Kerkhoffs G M M J, Struijs P A A, Marti R K, Assendelft W J J, Blankevoort L, van Dijk C N
Department of Orthopaedic Surgery, Academic Medical Center, G4-259, Amsterdam, Netherlands.
Cochrane Database Syst Rev. 2002(3):CD002938. doi: 10.1002/14651858.CD002938.
Acute lateral ankle ligament ruptures are common problems in present health care. Early mobilisation and functional treatment are advocated as a preferable treatment strategy. However, functional treatment comprises a broad spectrum of treatment strategies and as of yet no optimal strategy has been identified.
The objective of this review is to assess different functional treatment strategies for acute lateral ankle ligament ruptures in adults.
We searched the Cochrane Musculoskeletal Injuries Group specialised register (December 2001), the Cochrane Controlled Trials Register (The Cochrane Library, Issue 4, 2001), MEDLINE (1966 to May 2000), EMBASE (1980 to May 2000), CURRENT CONTENTS (1993 to 1999), BIOSIS (to 1999), reference lists of articles, and contacted organisations and researchers in the field.
Randomised clinical trials describing skeletally mature individuals with an acute lateral ankle ligament rupture and comparing different functional treatment strategies were evaluated for inclusion.
Two reviewers independently assessed the quality of included trials and extracted relevant data on treatment outcome. Where appropriate, results of comparable studies were pooled. Individual and pooled statistics are reported as relative risks (RR) for dichotomous outcome and (weighted) mean differences (WMD) for continuous outcome measures with 95 per cent confidence intervals (95%CI). Heterogeneity between trials was tested using a standard chi-squared test.
Nine trials involving 892 participants were included. Lace-up ankle support had significantly better results for persistent swelling at short-term follow up when compared with semi-rigid ankle support (RR 4.19, 95% CI 1.26 to 13.98); elastic bandage (RR 5.48; 95% CI 1.69 to 17.76); and to tape (RR 4.07, 95% CI 1.21 to 13.68). Use of a semi-rigid ankle support resulted in a significantly shorter time to return to work when compared with an elastic bandage (WMD (days) 4.24; 95% CI 2.42 to 6.06); one trial found the use of a semi-rigid ankle support saw a significantly quicker return to sport compared with elastic bandage (RR 9.60; 95% CI 6.34 to 12.86) and another trial found fewer patients reported instability at short-term follow-up when treated with a semi-rigid support than with an elastic bandage (RR 8.00; 95% CI 1.03 to 62.07). Tape treatment resulted in significantly more complications, the majority being skin irritations, when compared with treatment with an elastic bandage (RR 0.11; 95% CI 0.01 to 0.86). No other results showed statistically significant differences.
REVIEWER'S CONCLUSIONS: The use of an elastic bandage has fewer complications than taping but appears to be associated with a slower return to work and sport, and more reported instability than a semi-rigid ankle support. Lace-up ankle support appears to be effective in reducing swelling in the short-term compared with semi-rigid ankle support, elastic bandage and tape. However, definitive conclusions are hampered by the variety of treatments used, and the inconsistency of reported follow-up times. The most effective treatment, both clinically and in costs, is unclear from currently available randomised trials.
急性外侧踝关节韧带断裂是当前医疗保健中常见的问题。提倡早期活动和功能治疗作为一种较好的治疗策略。然而,功能治疗包含广泛的治疗策略,目前尚未确定最佳策略。
本综述的目的是评估成人急性外侧踝关节韧带断裂的不同功能治疗策略。
我们检索了Cochrane肌肉骨骼损伤小组专门注册库(2001年12月)、Cochrane对照试验注册库(Cochrane图书馆,2001年第4期)、MEDLINE(1966年至2000年5月)、EMBASE(1980年至2000年5月)、《现刊目次》(1993年至1999年)、BIOSIS(至1999年)、文章参考文献列表,并联系了该领域的组织和研究人员。
评估纳入随机临床试验,这些试验描述骨骼成熟的急性外侧踝关节韧带断裂个体,并比较不同的功能治疗策略。
两名评价员独立评估纳入试验的质量,并提取有关治疗结果的相关数据。在适当情况下,合并可比研究的结果。个体和合并统计数据报告为二分结果的相对风险(RR)和连续结果测量的(加权)平均差(WMD),并带有95%置信区间(95%CI)。试验间的异质性使用标准卡方检验进行检验。
纳入9项试验,共892名参与者。与半刚性踝关节支撑相比,系带式踝关节支撑在短期随访时持续性肿胀方面有显著更好的结果(RR 4.19,95%CI 1.26至13.98);弹性绷带(RR 5.48;95%CI 1.69至17.76);以及胶带(RR 4.07,95%CI 1.21至13.68)。与弹性绷带相比,使用半刚性踝关节支撑导致恢复工作的时间显著缩短(WMD(天)4.24;95%CI 2.42至6.06);一项试验发现,与弹性绷带相比,使用半刚性踝关节支撑恢复运动的速度显著更快(RR 9.60;95%CI 6.34至12.86),另一项试验发现,与弹性绷带治疗相比,半刚性支撑治疗的患者在短期随访时报告不稳定的较少(RR 8.00;95%CI 1.03至62.07)。与弹性绷带治疗相比,胶带治疗导致的并发症显著更多,大多数为皮肤刺激(RR 0.11;95%CI 0.01至0.86)。没有其他结果显示出统计学上的显著差异。
与胶带相比,弹性绷带的并发症较少,但似乎与恢复工作和运动的速度较慢以及比半刚性踝关节支撑报告的不稳定情况更多有关。与半刚性踝关节支撑、弹性绷带和胶带相比,系带式踝关节支撑在短期内似乎能有效减轻肿胀。然而,所用治疗方法的多样性以及报告的随访时间不一致阻碍了得出明确结论。从目前可用的随机试验中尚不清楚临床上和成本方面最有效的治疗方法。