Glazener C M, Lapitan M C
Health Services Research Unit (Foresterhill Lea), University of Aberdeen, Foresterhill, Aberdeen, Scotland, UK, AB25 2ZD.
Cochrane Database Syst Rev. 2002(3):CD003195. doi: 10.1002/14651858.CD003195.
Urodynamic tests are used to investigate people who have urinary incontinence or other urinary symptoms in order to make a definitive objective diagnosis. The aim is to help to select the treatment most likely to be successful. The investigations are invasive and time consuming.
The objective of this review was to discover if treatment according to a urodynamic-based diagnosis led to clinical improvements in urinary incontinence, compared to treatment based on history and examination.
We searched the Cochrane Incontinence Group trials register. Date of the most recent search: April 2002.
Randomised and quasi-randomised trials comparing clinical outcomes in groups of people who were and were not investigated using urodynamics, or comparing one type of urodynamics against another.
Two reviewers independently assessed trial quality and extracted data. Authors of one study were contacted for more information, including adverse effects.
Two small trials involving 128 women were included. In one small trial, women who were investigated with urodynamics were more likely to receive active treatment with drugs or surgery. However, the numbers in both trials were too small to determine if this affected clinical outcomes such as a reduction in incontinence.
REVIEWER'S CONCLUSIONS: A larger definitive trial is needed, in which people are randomly allocated to management according to urodynamic findings or to standard management based on history and clinical examination.
尿动力学检查用于对患有尿失禁或其他泌尿系统症状的患者进行检查,以做出明确的客观诊断。目的是帮助选择最有可能成功的治疗方法。这些检查具有侵入性且耗时。
本综述的目的是探究与基于病史和体格检查的治疗相比,根据尿动力学诊断进行治疗是否能使尿失禁的临床症状得到改善。
我们检索了Cochrane尿失禁小组试验注册库。最近一次检索日期:2002年4月。
随机和半随机试验,比较使用和未使用尿动力学检查的人群组的临床结局,或比较一种尿动力学检查方法与另一种方法。
两名综述作者独立评估试验质量并提取数据。联系了一项研究的作者以获取更多信息,包括不良反应。
纳入了两项涉及128名女性的小型试验。在一项小型试验中,接受尿动力学检查的女性更有可能接受药物或手术的积极治疗。然而,两项试验中的样本量都太小,无法确定这是否会影响诸如尿失禁减轻等临床结局。
需要进行一项更大规模的确证性试验,将患者根据尿动力学检查结果随机分配至相应治疗组,或根据病史和临床检查进行标准治疗。