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膀胱结石男性良性前列腺增生的非手术治疗

Nonsurgical management of benign prostatic hyperplasia in men with bladder calculi.

作者信息

O'Connor R Corey, Laven Brett A, Bales Gregory T, Gerber Glenn S

机构信息

Section of Urology, Department of Surgery, University of Chicago Hospitals, Chicago, Illinois 60637, USA.

出版信息

Urology. 2002 Aug;60(2):288-91. doi: 10.1016/s0090-4295(02)01698-9.

Abstract

OBJECTIVES

To assess the outcome of men with bladder calculi who did not undergo transurethral resection of the prostate after endoscopic stone removal. Bladder calculi associated with benign prostatic hyperplasia (BPH) have historically been an absolute indication for transurethral resection of the prostate.

METHODS

A retrospective analysis of the results of 23 men who underwent endoscopic removal of bladder calculi with subsequent medical management of BPH symptoms was performed. Inclusion criteria included men with bladder stones secondary to BPH, serum creatinine 1.6 mg/dL or less, no evidence of hydronephrosis, and no history of acute urinary retention or neurogenic bladder. The International Prostate Symptom Score and postvoid residual urine volume before and after treatment and the incidence of bladder stone recurrence and associated complications were recorded. All patients were treated with either an alpha-receptor blocker or alpha-receptor blocker and finasteride after bladder stone removal.

RESULTS

The follow-up after endoscopic removal of the bladder calculi averaged 30.0 months (range 6 to 96). The International Prostate Symptom Score before and after treatment was 18.3 and 9.4 (P <0.01), respectively. The postvoid residual urine volume before and after treatment was 354 and 179 mL (P <0.01), respectively. Urinary tract infection, acute urinary retention, recurrent calculi, chronic renal insufficiency, or renal failure developed in 21.7% (n = 5), 17.4% (n = 4), 17.4% (n = 4), 4.3% (n = 1), and 0% (n = 0) of the 23 men, respectively. Overall, 18 (78%) did not have any complications.

CONCLUSIONS

Many men with bladder stones can be successfully and safely treated with transurethral stone removal and medical management of BPH.

摘要

目的

评估经内镜取石术后未接受经尿道前列腺切除术的膀胱结石男性患者的治疗结果。与良性前列腺增生(BPH)相关的膀胱结石一直以来都是经尿道前列腺切除术的绝对指征。

方法

对23例行内镜下膀胱结石取出术并随后进行BPH症状药物治疗的男性患者的结果进行回顾性分析。纳入标准包括继发于BPH的膀胱结石男性患者、血清肌酐1.6mg/dL或更低、无肾积水证据、无急性尿潴留或神经源性膀胱病史。记录治疗前后的国际前列腺症状评分和排尿后残余尿量,以及膀胱结石复发率和相关并发症的发生率。所有患者在膀胱结石取出术后均接受α受体阻滞剂或α受体阻滞剂加非那雄胺治疗。

结果

内镜下膀胱结石取出术后的随访时间平均为30.0个月(范围6至96个月)。治疗前后的国际前列腺症状评分分别为18.3和9.4(P<0.01)。治疗前后的排尿后残余尿量分别为354mL和179mL(P<0.01)。23名男性患者中分别有21.7%(n=5)、17.4%(n=4)、17.4%(n=4)、4.3%(n=1)和0%(n=0)发生尿路感染、急性尿潴留、结石复发、慢性肾功能不全或肾衰竭。总体而言,18例(78%)未出现任何并发症。

结论

许多膀胱结石男性患者可通过经尿道结石取出术和BPH的药物治疗获得成功且安全的治疗。

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